R. A. Fisher. The relevance of the genetical theory of natural selection


  • Paola Monari Alma Mater Studiorum - Università di Bologna




Starting from the main statement that “. . . natural selection is not evolution. . . ”, R.A. Fisher built the foundation of the genetic theory of population in his famous work Genetical Theory of Natural Selection (1930). He rewrote the scientific paradigm proposed by Darwin in statistical terms using the calculus of probability and, most importantly, statistics. The key to his formal transposition is in the analysis of variance inwhich Fisher interpreted as phenomenical variability by means of random variability: this completely original result would become a fundamental chapter of statisticalmethod. It is not by chance that at the same time he published his statistical method for research workers in which the analysis of variance dominated his primary elements of the design of experiments.


F. AYALA (1982). Population and evolutionary genetics. The Benjamin Cummings Publisher, Menlo Park.

L. BOLTZMANN (1905). Populäre Schriften. J.A. Barth, Leipzig. Reprinted in 1919 and 1925.

M. BORN (1959). Natural philosophy of cause and chance. Cambridge University Press.

C. DARWIN (1845). Life and Letters of Charles Darwin. John Murray, London.

C. DARWIN (1872). On the origin of species by means of natural selection, or the preservation of favoured races in the struggle for life. John Murray, London.

R. FISHER (1930a). The genetical theory of natural selection. Clarendon Press, Oxford.

R. FISHER (1930b). Statistical method for research workers. Oliver and Boyd, Edinburgh.

R. FISHER (1935, 1966). The design of experiments. Oliver and Boyd, Edinburgh.

R. FISHER (1936). The use of multiple measurements in taxonomic problems. Ann. Eug., 7.

R. FISHER (1941). Average effect and average excess of a gene substitution. Ann. Eug., 11.

R. FISHER (1953). Population genetics. Proc. Roy. Soc. B, 141.

F. GALTON (1889). Natural inheritance. MacMillan, London.

J.HALDANE (1924–27). A mathematical theory of natural and artificial selection. Proc. Cambridge Phil. Soc., 23.

G. HARDY (1908). Mendelian proportion in a mixed population. Science, 28.

T. HUXLEY (1854). On the educational value of the natural history sciences. Collected Essays, III.

M. KENDALL (1963). Ronald aylmer fisher, 1890–1962. Biometrika, 50.

M. KENDALL (1970). Ronald aylmer fisher, 1890–1962. In E. PEARSON, M. KENDALL (eds.), Studies in the History of Statistics and Probability, Charles Griffin and Co., London.

M. KIMURA (1964). Diffusion models in population genetics. Methuen, London.

T. MATHUS (1798). Essay on principle of population. London.

G. MENDEL (1866). Versuche uber pflanzenhybriden. Verhan. Naturf. Ver. Brunn, IV.

P. MONARI, I. SCARDOVI (1989). I fondamenti statistici dell’equilibrio genetico nelle popolazioni. Ed.Martello, Milano.

J.MONOD (1970). Le hazard et la nécessité. Le Seuil, Paris.

K. PEARSON (1903–04). Mathematical contribution to the theory of evolution. Trans. Roy. Soc., 21–22.

I. SCARDOVI (1982). The idea of chance in statistical intuition of natural variability. Genus, 3–4.

I. SCARDOVI (1983). Chance and order in a statistical picture of life. Epistemologia, VI, 2.

E. SCHRÖDINGER (1967). What is life?: the physical aspect of the living cell; Mind and matter. Cambridge University Press.

L. C. SFORZA, A. BODMER (1971). The genetic of human population. Freeman, San Francisco.

S.WRIGHT (1931). Evolution in mendelian populations. Genetics, 16.




How to Cite

Monari, P. (2009). R. A. Fisher. The relevance of the genetical theory of natural selection. Statistica, 69(2/3), 129–141. https://doi.org/10.6092/issn.1973-2201/3552